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Type I cytokine receptors are transmembrane receptors expressed on the surface of cells that recognize and respond to cytokines with four α-helical strands. These receptors are also known under the name ''hemopoietin receptors'', and share a common amino acid motif (WSXWS) in the extracellular portion adjacent to the cell membrane. Members of the type I cytokine receptor family comprise different chains, some of which are involved in ligand/cytokine interaction and others that are involved in signal transduction. ==Signal transduction chains== The signal transducing chains are often shared between different receptors within this receptor family. * The IL-2 receptor common gamma chain (also known as CD132) is shared between: * * IL-2 receptor * * IL-4 receptor * * IL-7 receptor * * IL-9 receptor * * IL-13 receptor * * IL-15 receptor * The common beta chain (CD131 or CDw131) is shared between the following type I cytokine receptors: * *GM-CSF receptor * *IL-3 receptor * *IL-5 receptor. * The gp130 receptor ((130 )) (also known as gp130, IL6ST, IL6-beta or CD130) is shared between: * * IL-6 receptor * * IL-11 receptor * *IL-12 receptor * *IL-27 receptor * * Leukamia inhibitory factor receptor * * Oncostatin M receptor 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Type I cytokine receptor」の詳細全文を読む スポンサード リンク
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